{"product_id":"lipid-support-complex","title":"Lipid Support Complex","description":"\u003cp\u003eBenefits \u0026amp; Features\u003cbr\u003e\n• Supports hepatic fat metabolism‡\u003c\/p\u003e\n\n\u003cp\u003e• Reduces oxidative stress‡\u003c\/p\u003e\n\n\u003cp\u003e• Supports vascular health‡\u003c\/p\u003e\n\n\u003cp\u003e• Promotes healthy uric acid levels‡\u003c\/p\u003e\n\n\u003cp\u003e• Clinically studied BergacynFF®\u003c\/p\u003e\n\n\u003cp\u003eIndications\u003cbr\u003e\n• Ages 18 and up\u003c\/p\u003e\n\n\u003cp\u003e• Patients seeking support for healthy liver fat metabolism‡\u003c\/p\u003e\n\n\u003cp\u003e• Patients seeking support for healthy uric acid levels or oxidative stress‡\u003c\/p\u003e\n\n\u003cp\u003eSuggested Use\u003cbr\u003e\nAs a dietary supplement, take 2 capsules daily with meals, or as directed by a health care professional.\u003c\/p\u003e\n\n\u003cp\u003eScience \u0026amp; Research\u003cbr\u003e\nVerifiable Science\u003cbr\u003e\nLipid Support Complex supports hepatic fat metabolism with a combination of berberine and clinically studied BergacynFF®, a patented extract blend of bergamot citrus and Cynara cardunculus. BergacynFF® supports lipid metabolism in the liver, with the added benefits of promoting healthy uric acid levels, decreasing oxidative stress and supporting vascular endothelial health.1-4\u003c\/p\u003e \n\n\u003cp\u003eIn a randomized, double blind, placebo-controlled clinical study involving 102 subjects, BergacynFF® (600 mg\/day) for 12 weeks resulted in significant support for liver fat metabolism, assessed by CAP scores.2\u003c\/p\u003e \n\n\u003cp\u003eIn a randomized, double blind, placebo-controlled clinical study involving 80 subjects, BergacynFF® (600 mg\/day) significantly improved serum markers of oxidative stress, with a reduction in circulating malondialdehyde (MDA) coupled with an increase in glutathione peroxidase (GPx) and superoxide disumutase (SOD) levels after 16 weeks. Supplementation also supported vascular endothelial function.4\u003c\/p\u003e \n\n\u003cp\u003eThis formula also provides berberine, an alkaloid that moderates lipid accumulation in liver cells in vitro.5-8\u003c\/p\u003e \n\n\u003cp\u003eIn preclinical models, berberine activates hepatic AMP kinase (AMPK) and sirutin 1 (SIRT1), which play important roles in supporting fat utilization in moderating fat synthesis in the liver.7, 8-10‡\u003c\/p\u003e\n\n\u003cp\u003eReferences\u003cbr\u003e\nFerro Y, et al. Medicina (Kaunas). 2022 Nov 26;58(12):1728.\u003cbr\u003e\nFerro Y, et al. Front Endocrinol (Lausanne). 2020 Aug 11;11:494.\u003cbr\u003e\nParafati M, et al. J Nutr Biochem. (2015) 26:938– 48.\u003cbr\u003e\nMusolino V, et al. J Tradit Complement Med. 2020 Feb 8;10(3):268-274.\u003cbr\u003e\nXu X, et al. FASEB J. 2019 Jun;33(6):7289-7300.\u003cbr\u003e\nIonita-Radu F, et al. Int J Mol Sci. 2024 Apr 10;25(8):4201.\u003cbr\u003e\nYu M, et al. Int J Biol Sci. 2021 Apr 12;17(7):1693-1707.\u003cbr\u003e\nZhu X, et al. Free Radic Biol Med. 2019 Sep;141:192-204.\u003cbr\u003e\nSmith BK, et al. Am J Physiol Endocrinol Metab. 2016 Oct 1;311(4):E730-E740.\u003cbr\u003e\nTian C, et al. Pharmacol Res. 2024 May;203:107155.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":53129817063648,"sku":null,"price":57.0,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.saveusrx.com\/products\/lipid-support-complex","provider":"Saveusrx","version":"1.0","type":"link"}