{"product_id":"vitamin-d3-k2-120s","title":"Vitamin D3 \u0026 K2 120's","description":"\u003cp\u003eBenefits \u0026amp; Features\u003cbr\u003e\n• Promotes healthy calcium utilization to maintain bone health‡\u003c\/p\u003e\n\n\u003cp\u003e• Supports vascular tissue to support healthy arterial calcium balance and vascular elasticity‡\u003c\/p\u003e\n\n\u003cp\u003e• Supports immune function with vitamin D3‡\u003c\/p\u003e\n\n\u003cp\u003e• Provides vitamin D3 and vitamin K2 in one convenient capsule\u003c\/p\u003e\n\n\u003cp\u003e• 100 mcg of biologically active all-trans vitamin K2 (MK-7) per capsule\u003c\/p\u003e\n\n\u003cp\u003e• Made with hypoallergenic ingredients\u003cbr\u003e\n \u003cbr\u003e\nIndications\u003cbr\u003e\n• Ages 18 and up\u003c\/p\u003e\n\n\u003cp\u003e• Bone and vascular health support‡\u003c\/p\u003e\n\n\u003cp\u003eSuggested Use\u003cbr\u003e\nAs a dietary supplement, take 1 capsule daily, with a meal or as directed by a health professional.\u003c\/p\u003e\n\n\u003cp\u003eVerifiable Science\u003cbr\u003e\nVitamin K2 (menaquinone-7) is a fat-soluble nutrient with an important role in maintaining arterial calcium balance and vascular elasticity.1-12\u003c\/p\u003e \n\n\u003cp\u003eIn a systematic review involving five studies, higher intakes of vitamin K2 were associated with cardiovascular health.10\u003c\/p\u003e \n\n\u003cp\u003eIn an observational study involving 564 postmenopausal women, higher intake of vitamin K2 was associated with calcium balance in the vascular tissue.8\u003c\/p\u003e \n\n\u003cp\u003eOne of the primary functions of vitamin K2 is to support the carboxylation of matrix Gla-protein (MGP), a key protein involved in calcium balance.11\u003c\/p\u003e \n\n\u003cp\u003eAccordingly, several studies indicate that Vitamin K2 also supports proper utilization of calcium in bone. Clinical research indicates that obtaining adequate amounts helps to maintain bone health.1-6\u003c\/p\u003e \n\n\u003cp\u003eVitamin K2 and vitamin D3 both participate in the regulation of osteocalcin, a biomarker of bone formation.1,13‡\u003c\/p\u003e\n\n \u003cbr\u003e\n\u003cp\u003eReferences\u003cbr\u003e\n1. Gropper SAS, Smith JL, Groff JL. Advanced Nutrition and Human Metabolism. 5th Ed. Chapter 10, pp. 412-414. Wadsworth\/Cengage Learning, Australia. c.2009.\u003c\/p\u003e\n\n\u003cp\u003e2. El Borolossy R, El-Farsy MS. Eur J Clin Nutr. 2022 Jun;76(6):848-854.\u003c\/p\u003e\n\n\u003cp\u003e3. Qiu C, Zheng H, Tao H, et al. Mol Cell Biochem. 2017 Sep;433(1-2):149-159.\u003c\/p\u003e\n\n\u003cp\u003e4. Yamaguchi M, Sugimoto E, Hachiya S. Mol Cell Biochem. 2001 Jul;223(1-2):131-7.\u003c\/p\u003e\n\n\u003cp\u003e5. Zhang Y, Liu Z, Duan L, et al. Calcif Tissue Int. 2020 May;106(5):476-485.\u003c\/p\u003e\n\n\u003cp\u003e6. Knapen MH, Drummen NE, Smit E, et al. Osteoporos Int. 2013 Sep;24(9):2499-507.\u003c\/p\u003e\n\n\u003cp\u003e7. Knapen MH, Braam LA, Drummen NE, et al. Thromb Haemost. 2015 May;113(5):1135-44.\u003c\/p\u003e\n\n\u003cp\u003e8. Beulens JW, Bots ML, Atsma F, et al. Atherosclerosis. 2009 Apr;203(2):489-93.\u003c\/p\u003e\n\n\u003cp\u003e9. Mansour AG, Hariri E, Daaboul Y, et al. J Am Soc Hypertens. 2017 Sep;11(9):589-597.\u003c\/p\u003e\n\n\u003cp\u003e10. Rees K, Guraewal S, Wong YL, et al. Maturitas. 2010 Oct;67(2):121-8.\u003c\/p\u003e\n\n\u003cp\u003e11. Dalmeijer GW, van der Schouw YT, Magdeleyns E. Atherosclerosis. 2012 Dec;225(2):397-402.\u003c\/p\u003e\n\n\u003cp\u003e12. Vermeer C and Vik H. Vascul Dis Ther. 2020;5: doi: 10.15761\/VDT.1000179.\u003c\/p\u003e\n\n\u003cp\u003e13. Gigante A, Brugè F, Cecconi S, et al. J Tissue Eng Regen Med. 2015 Jun;9(6):691-701.\u003c\/p\u003e","brand":"Pure Encapsulations","offers":[{"title":"Default Title","offer_id":53129833447648,"sku":null,"price":33.73,"currency_code":"USD","in_stock":true}],"url":"https:\/\/www.saveusrx.com\/products\/vitamin-d3-k2-120s","provider":"Saveusrx","version":"1.0","type":"link"}